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Can Tylenol Really Relieve Hurt Feelings?

Among participants who had high levels of self-reported BPD features, those in the acetaminophen group showed more trust in their partners than those who had taken a placebo.

Can Tylenol Really Relieve ‘Hurt Feelings?’

Researchers say the ingredient acetaminophen can lessen extreme emotional responses, allowing people to get over rejection and other social feelings.

Is it possible that Tylenol can help alleviate not just physical pain, but social pain as well?

A growing body of research suggests that acetaminophen, the active ingredient in Tylenol, may help dampen emotional responses.

In a study published earlier this fall, researchers from The Ohio State University found evidence that acetaminophen may reduce behavioral distrust in people with high levels of borderline personality disorder (BPD) features.

The investigators recruited 284 undergraduate students, each of whom they assessed for BPD features using a self-reported scale.

Following a double-blind procedure, the researchers randomly assigned each participant to receive either 1,000 milligrams of acetaminophen or a placebo.

Afterward, they asked participants to take part in an economic trust game.

Among participants who had high levels of self-reported BPD features, those in the acetaminophen group showed more trust in their partners than those who had taken a placebo.

Among participants with low levels of BPD features, there were no differences in trust observed between those who had taken acetaminophen and those who had taken a placebo.

“In line with past research, we found that people who self-reported higher levels of characteristics associated with BPD entrusted less money to anonymous partners,” Ian Roberts, PhD, a postdoctoral fellow at the University of Toronto and a lead study author, told Healthline.

“However,” he continued, “our study also found that, for those higher on BPD features, this distrust was reduced when they had been given acetaminophen as compared to a placebo.”


A Horrifying Week with My Borderline Personality Disorder

I google “how to hang yourself from a radiator” in the waiting room before ducking out for a quick cry.

BON: I stumbled on this over the weekend. It’s worth the time to read. It really captures the desperation of BPD.

A Horrifying Week with My Borderline Personality Disorder

by Heather Sleepy
OCT 23, 2015

I was diagnosed with Borderline Personality Disorder last December, but that was only the beginning of my troubles. This is my diary of what came after.


Monday is relatively chill. I manage to make it to work for 10 AM, only 30 minutes late. I’m 100 percent sure my boss thinks I’m a dick. He most definitely treats me unfavorably and this is most definitely because I’m late nine times out of 10, recurringly incapable of hitting deadline, and I’m pretty sure he’s aware I allocate too much of the working day to sobbing in the bathroom. Nethertheless, he doesn’t say anything to me.

Before 1pm I’ve already puked once from anxiety and deleted my Facebook profile for the zillionth time this week. Around 3 PM I phone my ex-boyfriend and beg him to come back. He says no and asks me to go to the bathroom, stuff my hands in my pants and send him a photo. I do. It stops the shaking and sweating till about 6.30 PM when I get back home. My room’s a mess. Swollen with moldy plates, grubby underwear, and flies. I slink into bed, whack on Rick and Morty, neck some sleeping pills and wake up on Tuesday.


Work is impeccably whack today. I manage to make it in on time and even sneak in a two hour lunch. By midday I’m feeling unbearably anxious so I convince a friend to meet me for lunch. We hit a restaurant called Lyle’s and I have a bottle of wine, goat’s heart, and brisket. I check my phone 42 times but am feeling far less anxious upon my return to work despite being undeniably turnt and unable to do anything productive for the remaining duration of the day.


The Death Treatment

He recently approved the euthanasia of a twenty-five-year-old woman with borderline personality disorder who did not “suffer from depression in the psychiatric sense of the word,” he said. “It was more existential; it was impossible for her to have a goal in this life.”

The Death Treatment
When should people with a non-terminal illness be helped to die?

Letter from Belgium JUNE 22, 2015 ISSUE

In her diary, Godelieva De Troyer classified her moods by color. She felt “dark gray” when she made a mistake while sewing or cooking. When her boyfriend talked too much, she moved between “very black” and “black!” She was afflicted with the worst kind of “black spot” when she visited her parents at their farm in northern Belgium. In their presence, she felt aggressive and dangerous. She worried that she had two selves, one “empathetic, charming, sensible” and the other cruel.

She felt “light gray” when she went to the hairdresser or rode her bicycle through the woods in Hasselt, a small city in the Flemish region of Belgium, where she lived. At these moments, she wrote, she tried to remind herself of all the things she could do to feel happy: “demand respect from others”; “be physically attractive”; “take a reserved stance”; “live in harmony with nature.” She imagined a life in which she was intellectually appreciated, socially engaged, fluent in English (she was taking a class), and had a “cleaning lady with whom I get along very well.”

Godelieva, who taught anatomy to nurses, had been in therapy since she was nineteen. With each new doctor, she embraced the therapeutic process anew, adopting her doctor’s philosophy and rewriting her life story so that it fit his theory of the mind. She continually dissected the source of her distress. “I am confronted almost daily with the consequences of my childhood,” she wrote to her mother. She’d wanted to be a historian, but her father, domineering and cold, had pressured her to be a doctor. Her mother, who was unhappy in her marriage, reminded her of a “slave.” “New insight,” she wrote in her diary. “Do not want to always nod yes like her and be self-effacing.”

Godelieva was preoccupied with the idea that she would replicate her parents’ mistakes with her own children. She married when she was twenty-three, and had two children. But the marriage was tumultuous and ended in divorce, in 1979, when her son was three and her daughter was seven. Two years later, their father, Hendrik Mortier, a radiologist, committed suicide. As a single parent, Godelieva was overwhelmed. In a diary entry from 1990, when her children were teen-agers, she instructed herself to “let my children be themselves, respect them in their individuality.” But she found herself fighting with her daughter, who was independent and emotionally distant, and depending on her son, Tom, a “victim of my instability,” she wrote. She worried, she told her psychologist, that her children were “now paying for all that has happened generations earlier.”


Study shows trend of prescribing opioids to patients with a comorbidity of borderline personality disorder increased over time

The results also suggest that these borderline patients may be particularly sensitive to physical pain–mirroring their well-known heightened sensitivity to emotional pain.

Study shows trend of prescribing opioids to patients with a comorbidity of borderline personality disorder increased over time
January 23, 2014 | By Joe Wiegel – PCLS President

Patients with borderline personality disorder are being prescribed opioid pain medication at increasing rates according to a recent follow-up study by Drs. Frankenburg, Fitzmaurice and Zanarini.

The researchers attempted to determine the rate of use of prescription opioid medications by patients with borderline personality disorder and compare that to the rate reported by the control group during a 10-year follow-up. In addition, they attempted to determine the most clinically relevant predictors of prescription opioid use among borderline patients. They assessed the study participants at 6-year follow-up and 5 contiguous follow-up waves that were 2 years apart. All participants had a family history of psychiatric disorder assessment at the baseline as well as semi-structured interviews with proven psychometric properties including: the Medical History and Services Utilization Interview, the Structured Clinical Interview for DSM-III-R Axis I Disorders, and the Revised Family History Questionnaire.

Continue reading Study shows trend of prescribing opioids to patients with a comorbidity of borderline personality disorder increased over time

Pain Really Is All In Your Head And Emotion Controls Intensity

Positive emotions — like feeling calm and safe and connected to others — can minimize pain. But negative emotions tend to have the opposite effect.

Pain Really Is All In Your Head And Emotion Controls Intensity

FEBRUARY 18, 2015 4:03 PM ET


When you whack yourself with a hammer, it feels like the pain is in your thumb. But really it’s in your brain.

That’s because our perception of pain is shaped by brain circuits that are constantly filtering the information coming from our sensory nerves, says David Linden, a professor of neuroscience at Johns Hopkins University and author of the new book Touch: The Science of Hand, Heart, and Mind.

“The brain can say, ‘Hey that’s interesting. Turn up the volume on this pain information that’s coming in,’ ” Linden says. “Or it can say, ‘Oh no — let’s turn down the volume on that and pay less attention to it.’ “

Read the Rest of the Story and Listen to the Radio Program

How to Get Through Crisis

Crisis response coping is crucial for individuals with poor emotion regulation

How to Get Through Crisis
~ 2 min read

Distress is a fact of life. It’s a wide range of triggers: it’s not always our turn, or we have bad luck, or we make a bad decision and have to suffer the consequences or we experience oppression and injustice and so on. How upsetting these different degrees of distress are depends not only on the magnitude of the event, it depends on us—the same event may be annoying to one person and catastrophic to another. Most of us have different ways of dealing with different levels of distress. People who are more emotionally vulnerable don’t differentiate as well, and actually experience any amount as intolerable.

How DBT teaches distress tolerance

This might be the most misunderstood skill set in evidence-based practice. Radical acceptance was initially a very challenging idea: that one must complete accept reality as it is without being driven to change it in order to move forward. This doesn’t mean that we can’t make changes or that we shouldn’t try, but that to do so we first must accept things as they are.

If this sounds familiar that may be because mindfulness has become a lot more popular in psychotherapy since the original DBT text was written. In fact, mindfulness has become the basis of more than one evidence-based therapy. But not all advances in evidence-based practice made understanding DBT helpful. In fact, a better understanding of anxiety is the source of objections to the other set of DBT distress tolerance skills.