• Biology,  Shame

    Versions of Shame

    Versions of Shame Version A) they are just born that way. THEY are not even sure of what they are ashamed of. They carry around three core beliefs: “The world is dangerous and malevolent”, “I am powerless and vulnerable” and “I am inherently unacceptable.” But they don’t know WHY – they have just always been that way. The only reason that I can gather is that they have labile emotions and they lead to an unstable sense of self. That instability is what they are ashamed of (and scared anyone and everyone will know). It’s like a nightmare in which you’ve pissed your pants and you hope to god no…

  • Biology,  Borderline Personality Disorder

    Diseases of the Mind

    This is a quote from “Decartes’ Error” by Antonio Damasio: The distinction between diseases of the “brain” and the “mind”, between “neurological” problems and “psychological” or “psychiatric” ones, is an unfortunate cultural inheritance that permeates society and medicine. It reflects a basic ignorance of the relation between brain and mind. Diseases of the brain are seen as tradgedies visited on people who cannot be blamed for their conditions, while diseases of the mind, especially those that affect conduct and emotion, are seen as social inconveniences for which sufferers have much to answer. Individuals are to be blamed for their character flaws, defective emotional modulation, ans so on; lack of willpower…

  • Biology

    Biology of Borderline Personality Disorder

    Can BPD be inherited? Here’s an article on the biological aspects of BPD. Genetic studies of monozygotic and dizygotic twins suggest that there may be genetic factors for these dimensions of emotional reactivity and impulsive aggression, while there does not appear to be a heritability for BPD as a category. Family members of BPD patients are more likely to demonstrate affective instability or impulsivity, although not necessarily both. Impulsivity and aggression seem to be heritable in studies of normal twins as well. It is noteworthy that in the studies of prolactin responses to fenfluramine, blunted prolactin response to fenfluramine in a patient is a better predictor of impulsivity and aggression…

  • Biology

    BPD: Emotional Dysregulation and MRI/fMRI

    A study, using an MRI, of BPD patients found: We believe that this hyper excitability in BPD patients, particularly in brain regions thought to be involved in generating emotions, is likely to put this patient group at high risk for experiencing episodes of abnormally intense and inappropriate negative emotions characteristic of ED. In support of our hypothesis, we also found that the level of amygdala activation to the Fearful, and Neutral faces in BPD patients is significantly correlated with diagnostic measures of emotional lability. So, what does this mean? If you “go calm” or “neutral” on the BP in your life, they will not understand it – their brain sees…