The scans revealed that those with BP were able to function quite normally under normal conditions, but when taxed, their brains were found to have to work harder than normal to keep up. Those with BPD on the other hand, showed heightened activity in the amygdala, a part of the brain normally associated with fear [...]
The hallmark symptom that people describe is emotion dysregulation — you’re happy one moment, and the next moment you’re feeling angry or sad or depressed. People with BPD can cycle through emotions, usually negative ones, quite rapidly.
New insights into the ‘borderline personality’ brain (link)
New work by University of Toronto Scarborough researchers gives the [...]
Now that we know the specific brain mechanisms associated with empathy, we can translate these findings into disease categories and learn why these empathic responses are deficient in neuropsychiatric illnesses, such as autism.
Specific Brain Region Tied to Empathy (read the Article at PsychCentral) By TRACI PEDERSEN Associate News Editor Reviewed by John M. Grohol, [...]
Personality disorders could be more effectively diagnosed by identifying and targeting the disrupted neurobiological systems where the disorders originate, report Cornell researchers.
New approach could more effectively diagnose personality disorders (link) February 20th, 2012 in Psychology & Psychiatry
(Medical Xpress) — Personality disorders could be more effectively diagnosed by identifying and targeting the disrupted neurobiological [...]
I spoken about mentalization on this site before. Since I’ve lately been on a TED talk kick, mainly watching TED talks about neuroscience, I wanted to post this one from Rebecca Saxe which is called “How we read each other’s minds”. It is basically describing the process of mentalizing and how a certain part of [...]
Depressive, impulsive and antisocial symptoms caused by severe chronic stress during childhood are transmitted epigenetically from one generation to the next.
Epigenetic inheritance of the negative impact of stressful events across generations
Depressive, impulsive and antisocial symptoms caused by severe chronic stress during childhood are transmitted epigenetically from one generation to the next. This has [...]
“Much of it comes from self-destructive behaviors that are used to stop the horrible pain of dysphoria; anxiety, rage, depression and despair. When an individual behaves out-of-control, in a manner that’s inconsistent with their beliefs or normal choices, terrible self-hate develops. Additionally many individuals had low self-esteem and related problems since childhood and are in [...]
An article about the opioid system and the neurobiology of borderline personality disorder.
Neurobiology Informs Successful Psychotherapy for BPD
A common feature of all psychotherapies for borderline personality disorder is activation of the prefrontal cortex through reappraisal of painful affect states generated by a hyperactive amygdala.
Neurobiological research can help psychotherapists tailor talking [...]
Simon Baron-Cohen has been giving interviews about his new book The Science of Evil: On Empathy and the Origins of Cruelty in which he discusses “mind-blindness” in autism and the lack of empathy in other disorders, including BPD. Here is the text of the interview he gave to Time magazine. I have added emphasis on [...]
Genetics in Borderline Personality Disorder
I was reading an article called “Social cognition in borderline personality disorder: evidence for disturbed recognition of the emotions, thoughts, and intentions of others” and noticed a line in the article that said this: “Thus, in addition to high heritability of BPD (Torgersen et al., 2008), these results argue [...]