Those exhibiting personality traits associated with negative affect such as depression and anxiety (such as that found in BPD), non-conformity, impulsiveness, emotional instability, sensation-seeking and thrill-seeking, poor external locus of control, as well as low self-esteem, tend to be particularly susceptible to substance abuse disorders.
Personality disorders correlated with drug abuse, say researchers
Recent research suggests that drug addiction is frequently comorbid with personality disorders. According to Zimmerman and Coryell (1989), up to 43-77 percent of individuals with personality disorders qualify for a diagnosis of alcohol use disorder at some point in their lives. Likewise, Verheul and colleagues (1995, 1998) examined the co-incidence of personality disorders with substance abuse and found that 44 percent of individuals addicted to alcohol meet the criteria for a personality disorder. In addition to this, 77 percent of those who abuse opiates qualify for a diagnosis of a personality disorder. Cluster B personality disorders, such as borderline personality disorder, and antisocial personality disorder, were found to be particularly associated with substance abuse disorders.